ncibtep@nih.gov

Bioinformatics Training and Education Program

Variant Analysis: Experimental Design, Best Practices and Workflows

Variant Analysis: Experimental Design, Best Practices and Workflows

 When: Jun. 30th, 2022 2:00 pm - 4:00 pm

To Know

Where:
Online Webinar
Organizer:
BTEP
Presented By:
Justin Lack (NIAID CBR), Keyur Talsania (Bioinformatics Analyst IV, ABCS FNLCR)
This class has ended.

About this Class

Experimental Design Considerations in Variant Analysis
  • Germline vs Somatic
  • WGS vs WES
  • Sample sizes and statistical power
  • QC, variant annotation, and analysis considerations
Beyond GATK!
  • A survey of variant calling tools
  • The actual Best Practices for variant calling
  • Long read technology and germline variant calling
  • Tumor vs tumor-normal: performance and considerations
Structural variants ·     Long-read approaches for SV discovery/current WGS/WES Best Practices workflow
Meeting Link: https://cbiit.webex.com/cbiit/j.php?MTID=m7a7e36713b391012d5d3b800c983fc2c