The NIH HPC group plans, manages and supports high-performance computing systems specifically for the intramural NIH community. These systems include Biowulf, a 90,000+ processor Linux cluster; Helix, an interactive system for short jobs, Sciware, a set of applications for desktops, and Helixweb, which provides a number of web-based scientific tools. They provide access to a wide range of computational applications for genomics, molecular and structural biology, mathematical and graphical analysis, image analysis, and other scientific fields.

The majority of Helix/Biowulf services require the use of a command-line tools such as ssh to remotely access the system.

Details about such tools remote access programs can be found here.

A limited number of applications are available via a Web-based interface, and are listed here.


Accounts on the NIH Helix/Biowulf system are restricted to NIH employees and contractors as determined by inclusion in the NIH Enterprise Directory (

More information about getting an account can be found here.

Operational access is limited to those in the NIH Network.