Geneious is a DNA, RNA and protein sequence alignment, assembly and analysis software platform, integrating bioinformatic and molecular biology tools into a simple interface.
NGS Assembly (link is external)
- Assemble 454, SOLiD and Illumina
- Reference and de novo assembly
- Hybrid (mixed data) assembly
- Paired-end and mate pair assembly
- Velvet, Maq, Bowtie on Geneious Server™ (link is external)
Visualizations (link is external)
- 3D structures
- Sequences, alignments, assemblies
- Annotations, SNPs, restriction sites
- Phylogenetics trees
- Dot plot, virtual gel
- RNA secondary structure
Chromatogram Editing and Assembly (link is external)
- Chromatogram assembly of Sanger data
- Import Sequencher data from .CAF file
- Assemble by name
- Call secondary peaks
Geneious Biocode LIMS (link is external)
- Manage sequences in 96/384 well plates
- Import chromatograms & attach to plates
- Bin and trim chromatograms
- Verify Taxonomy vs Genbank
- Genbank submission (link is external)
- ClustalW (Greenbutton (link is external) enabled)
- MUSCLE and MAFFT alignment
- Translation and profile alignment
- MAUVE genome alignment
Phylogenetics (link is external)
- MrBayes (Greenbutton (link is external) enabled)
- PAUP* interface including ModelTest
- NJ, UPGMA and PhyML
- Bootstrapping and consensus trees
- Interactive tree viewing
- One-step multi-site Gateway cloning
- One-step insert fragment into vector
- Virtual gel viewer
- Restriction digest
- Show non-cutting enzymes
Primer Design (link is external)
- PCR primers and probes with Primer3
- Primers on alignments and assemblies
- Built-in primer database
- Test existing primers vs sequence
- Sequencing & multiplex primers (coming soon)
Database Search (link is external)
- BLAST and custom BLAST search
- Local search
- Sequence search
- Literature search
- Automated search agents
Predict, Manipulate and Annotate (link is external)
- ORFs, repeats, CpG islands
- SNPs, INDELs, low/high coverage
- Protein secondary structure
- Cleavage sites, transcription factors
- Antigenic regions, Pfam domains
Access Information:
Contact the NIH Help Desk: Telephone: 301-496-4357 (open 6:00 am – 6:00 pm)
Email: helpdesk@nih.gov
Web: http://support.nih.gov
Requirements
Access
Related