Key Pathway Advisor (KPA) is a web application for biological pathway analysis of OMICs data. This session will demonstrate using KPA to: explore the biological meaning of data; predict key protein activity changes that could be the root cause of gene expression alterations; understand how biological pathways are impacted by data; create hypotheses about new targets, mechanisms of action, biomarkers and disease associations; and align results with current knowledge of biomarkers and drug targets. Bioinformatics experience is not required to use this tool.