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Bioinformatics Training and Education Program

june, 2022

29jun11:00 am12:00 pmNext Generation Transcriptomics-based Precision Oncology

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Event Details

During this webinar, Computational Biologist Dr. Eytan Ruppin will present on “SELECT,” a computational approach that aims to identify clinically relevant synthetic lethal interactions, thereby harnessing them to predict patient response to cancer therapy from the bulk tumor transcriptome.

Tested on a broad collection of targeted and immunotherapy clinical trials, SELECT is predictive of patients’ response in 80% of those and in the recent multi-arm WINTHER clinical trial.

The session will also cover:

  • “MadHitter” and “PERCEPTION,” two new computational approaches for guiding precision cancer therapy based on single cell tumor transcriptomics.
  • future challenges that need to be addressed to further advance transcriptomics-based precision oncology, including the development of a new precision oncology expression-based approach starting from histopathological images.

The Data Science Seminar Series presents talks from innovators in the cancer research and informatics communities both within and outside of NCI.

Presenter:

Eytan Ruppin, M.D., Ph.D.

Dr. Ruppin is the chief and senior investigator of NCI’s Cancer Data Science Laboratory. He’s a trained computational biologist whose research is focused on developing and harnessing data science approaches for the integration of multi-omics data to better understand the pathogenesis of cancer, its evolution, and treatment.

 

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Time

(Wednesday) 11:00 am - 12:00 pm

Location

Online

Organizer

Data Science Seminar Series

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