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Bioinformatics Training and Education Program

september, 2021

27sep2:00 pm3:00 pmGenomic Data Commons Single Cell RNA-Seq Support

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Event Details

The NCI Genomic Data Commons’ (GDC) September webinar will introduce cancer researchers and bioinformaticians to the GDC’s single-cell RNA-Seq (scRNA-Seq) data workflow. Single cell sequencing is a powerful platform for studying tumor heterogeneity and the microenvironment.

During the webinar, GDC’s Drs. Bill Wysocki and Zhenyu Zhang will:

  • provide an overview of the GDC scRNA-Seq workflow and quality control.
  • demonstrate download of scRNA-Seq data generated from GDC workflows.
  • demonstrate (using Jupyter notebooks) how scRNA-Seq data can be analyzed using dimensionality reduction plots such as Uniform Manifold Approximation and Projection (UMAP) to:
    • visualize relationships between cells.
    • discover cell marker profiles and/or gene expression patterns of tumor-related genes.

As a data sharing platform within the NCI Cancer Research Data Commons (CRDC), the GDC supports user-submitted data, including scRNA-Seq data, that can be harmonized and made available to the research community. For additional information on how the GDC works with other components in the CRDC, visit datacommons.cancer.gov.

Speakers:

  • Bill Wysocki, Ph.D.

Dr. Wysocki is the director of User Services and Outreach for the GDC at the University of Chicago.

  • Zhenyu Zhang, Ph.D.

Dr. Zhang is the co-principal investigator of the GDC at the University of Chicago.

 

 

Register Here

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Time

(Monday) 2:00 pm - 3:00 pm

Location

Online

Organizer

NCI

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