Course Details

  • Date: June 30th, 2022 - June 30th, 2022
  • Time: 2:00 pm - 4:00 pm
  • Location: Online Webinar
  • Presenter(s): Justin Lack (NIAID CBR), Keyur Talsania (Bioinformatics Analyst IV, ABCS FNLCR)
Experimental Design Considerations in Variant Analysis
  • Germline vs Somatic
  • WGS vs WES
  • Sample sizes and statistical power
  • QC, variant annotation, and analysis considerations
Beyond GATK!
  • A survey of variant calling tools
  • The actual Best Practices for variant calling
  • Long read technology and germline variant calling
  • Tumor vs tumor-normal: performance and considerations
Structural variants
·     Long-read approaches for SV discovery/current WGS/WES Best Practices workflow