To Function or Not to Function
The functions of only a minority of genes in any species is known. And even in those cases the functional annotation is highly incomplete and largely devoid of context. At an even more fundamental level, how can we know whether a gene serves any relevant biological function in a given context? In this informal presentation we will discuss a few vignettes related to the broad questions of context-specific functions of genes, in a variety of contexts from bacterial response to drugs, normal tissues, and cancer.
Recording of the talk is here: https://cbiit.webex.com/cbiit/ldr.php?RCID=ec72d1923ffe18a82b63ed348b75be0c
Course Material 1: Sridhar_CCR-Ed-0220.pptx