Driven by the decreasing costs and increasing performance of next-generation sequencing (NGS) technologies, the amount of publicly available genomic data has grown exponentially in recent years. While most of the analyses of these data is done computationally, there are many instances where visual inspection of the original and/or processed data is invaluable. Such direct visualization can provide: “sanity checks” on computational results; novel biological insights; aid in communicating results; and a better understanding of the interplay between spatially related biological elements. These visualization tools are relevant whether one is interested in expression analysis (RNA-Seq), variant detection (Exome-Seq), protein binding (ChIP-Seq), or any other genome scale data.
This seminar will provide an overview of the available tools, and highlight useful features of some of the more popular genome browsers. Highlighted topics will include:
- An overview of the tools available – their strength and weaknesses and where to find them
- An overview of the different classes of browsers
- An discussion of the relevant file types accepted by most browsers
- Details on how to navigate the UCSC Genome Browser
- How to integrate your own or publically available data into browsers
- How to capture and share specific views of data
- How to get more detailed views of your data with tools like IGB and IGV and how to integrate them into other tools
- and more….