QIAGEN’s Ingenuity Pathway Analysis (IPA) allows for quick and easy biological interpretation using the results of your RNA-Seq differential expression analyses. IPA’s functionality is tied to an extensive, rich set of curated relationships in the Qiagen Knowledge Base and has been cited in >20,000 peer-reviewed articles. This session will focus on utilizing RNA-Seq data from a recent metastatic melanoma study and review how the simple graphical user interface can be used to import the results of a differential expression analysis to determine key biological endpoints, including pathways, predicted regulatory molecules, and functional impact, and compare these biological findings to public studies. These results can then be easily exported as tables and publication-ready figures.
Requests for IPA access may be made directly through the NCI Service Desk: https://service.cancer.gov/selfservice
Once they have an account, to access IPA web version, please click on https://analysis.ingenuity.com/pa
To install the new IPA desktop client, please do so at: https://analysis.ingenuity.com/pa/installer/select